Combination of tramadol or hydrocodone cause constipation?

Can the combination of tramadol or hydrocodone cause constipation?

Tramadol is in a drug class called opiate agonists. Tramadol is used for the management of moderate to moderately severe pain. Tramadol works by altering pain sensation in the body. The most common side effects with tramadol are: dizziness/vertigo; nausea; constipation; headache; sleepiness; vomiting; itching; central nervous system stimulation (i.e., nervousness, anxiety, agitation, continuous muscle contraction, euphoria, emotional instability, and hallucinations); lack or loss of strength and energy; sweating; upset stomach; dry mouth and diarrhea. According to tramadol’s prescribing information, in studies, constipation resulted in discontinuation of tramadol in 10% of people over the age of 75. Hydrocodone is in a drug class called opiate or narcotic analgesics (pain relievers) and antitussives (anti-cough). Hydrocodone is only available in medication formulations that contain other ingredients. Certain hydrocodone products are used to treat moderate to severe pain. Some other hydrocodone products are used to treat cough. Hydrocodone works to relieve pain by changing the way the brain and nervous system respond to pain. Hydrocodone helps to relieve cough by lessening brain activity that causes cough. Side effects with hydrocodone include: constipation; nausea; vomiting; drowsiness; dizziness; lightheadedness; fuzzy thinking; anxiety; being abnormally happy or sad; dry throat; trouble urinating; rash; itching; and narrowing of pupils. These are not complete lists of the side effects associated with tramadol and hydrocodone. There are many causes of constipation.